Burn Medical Care
Title: Artificial dermis offers wound care alternative.(Dermatologic Surgery)(Medical condition overview)
Date: 3/1/2007; Publication: Skin & Allergy News; Author: Evans, Jeff
VAIL, COLO. -- A bioengineered skin substitute may have applications in reconstructive surgery that extend beyond its indication for burn victims, Dr. Kapil Saigal said at a symposium sponsored by the American Academy of Facial Plastic and Reconstructive Surgery.
The recent development of biomaterials for head and neck reconstruction has provided alternatives to autologous skin transplantation, such as cadaveric allograft skin, xenografts, and bioengineered skin substitutes, said Dr. Saigal, a fourth-year resident in the department of otolaryngology-head and neck surgery at Jefferson Medical College, Philadelphia.
A biologic skin substitute can be used as a permanent replacement or as a temporary biologic dressing. These skin substitutes can decrease bacterial counts; slow the loss of water, proteins, and electrolytes from the wound; reduce pain and fever; help restore function and facilitate early motion; and prevent desiccation of vessels, tendons, and nerves.
Fewer data are available on the functionality of biological skin substitutes in reconstructive surgery man to burn treatment and chronic wound healing, he said. Integra artificial dermis is a composite bilayer dermal regeneration template that is used for skin replacement. It was approved by the Food and Drug Administration in 2003 for the treatment of life-threatening third-degree burns to provide immediate coverage for as much as 95% of body surface area.
The biomaterial is composed of a dermal replacement layer of a porous matrix of crosslinked bovine tendon collagen coated with a glycosaminoglycan (chondroitin-6-sulfate); a temporary epidermal layer of polysiloxane polymer (silicone) prevents moisture loss.
After Integra has been in place for 2-3 weeks, the template changes from its original color of pink to yellow or an orange-peach color, which indicates that the graft is vascularized and a new dermal-like layer has been generated. The epidermal polysiloxane layer can be removed so that a very thin epidermal autograft can be placed on the new dermis. Very little wound contraction occurs because of the thick dermal component, Dr. Saigal explained.
The template is thought to improve "fibroblast proliferation from the wound edges, while the addition of a glycosaminoglycan actually decreases the inflammatory component of wound healing and prevents the formation of granulation tissue," he said at the symposium, which also was sponsored by the American Society for Dermatologic Surgery and the American Society of Ophthalmic Plastic and Reconstructive Surgery.
Dr. Saigal reported that he and his associates have used Integra in 15 patients for wounds ranging from those on the eyelid to radiated scalp wounds with graft sizes of 10-140 [cm.sup.2]. Most of the reconstructions have been performed on an outpatient basis.
They have used the skin substitute to perform a delayed reconstruction after removal of a cutaneous malignancy, repair a defect after surgery for severe rhinophyma, cover wounds of the head and neck that were not amenable to primary or focal closure, and heal areas that have been irradiated or will be irradiated post-operatively The product may be useful in closing wounds in children and elderly patients, he suggested.
In a case series of seven patients with an average age of 70 years who received the Integra artificial dermis, 100% of the split-thickness skin grafts that were applied after a mean of about 5 weeks survived without any complications (Plast. Reconstr. Surg. 2005; 115:1010-7).
Other reports in the literature suggest that Integra has a better "take rate" in complicated wounds when it is combined with a vacuum-assisted closure or with fibrin glue, said Dr. Saigal, who disclosed that he and his colleagues have no financial interest in Integra.
Integra costs about $700-$900 per graft, he said.
BY JEFF EVANS
Senior Writer
COPYRIGHT 2007 International Medical News Group
This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group.
Burn Medical Care
BIOSKINCARE FOR SCAR TREATMENT
BIOSKINCARE™ has a two fold effect: (1) Degrades debris, damaged, abnormal and necrotic tissues & decongests the skin as it helps to dissolve all damaged structures into their amino-acid and other components by the action of enzymes. (2) Favors tissue regeneration.
It leaves your skin smooth, refreshed, soft and with use over a period of time it reduces contractures and takes away keloid, hypertrophic and all types of scars and blemishes: acne, scars, keratosis bumps, razor nicks and burns, actinic keratosis lesions, roughness, dryness, ezcema, dermatitis, the effects on the skin of radiotherapy for cancer, blisters, scrapes, cuts, and the list can go on and on... It clears and enhances the complexion.
Made in the USA. 50 grams = 1.76 oz
Save at least 20% off price & save on shipping costs
when you order more than one jar
One Bottle: $69.98
Two Bottles: $55.98 each
Ultra exfoliate rough scars and dull skin with BIOSKINEXFOL
Home microdermabrasion cream. Contains the same natural ingredients in BIOSKINCARE but infused with micro-crystals so that you may rub it with your finger tips to remove old, hard, and tough scars or stretch marks by a physical breakdown of the scar tissues. Best also for oily skin and aged skin, actinic keratosis scales and pitted acne scars. Not for keloids and not if your skin is still fragile (use BIOSKINCARE for a few months first to strengthen your skin). The compounded action of the physical abrasion and the enzymes in the cream liquefy damaged proteins more thoroughly helping to release amino-acids to aid in rebuilding damaged tissues quickly. Results are not only immediate, but compound over time and do not trigger inflamm-aging of delicate skin tissues.
Made in the USA. Two to Three Month's supply 120 grams = 4.23 oz
120 Gram Bottle: $89
Get rid of hiperpigmentation of scar areas and tissues and sun & age spots while reviving and protecting the skin from the effects of free radicals with BIO SKIN REJUVENATION
A deeply moisturizing natural skin care cream that replenishes the lipid barrier of the skin and triggers the repair of cells damaged by UV radiation and Free Radicals. Also gets rid of brown, sun and age spots, actinic keratosis scales and all types of skin blemishes. The same ingredients in BIOSKINCARE with an added natural substance that reduces melanin hyperpigmentation and a biomimetic peptide that inhibits the accumulation of melanin pigments.
One Month's Supply 1.76 oz., 50 Gram Bottle: $79
Toll Free USA & Canada
The Biological Skin Treatment Serum
Our products contain a biological serum created by a living creature to (a) take care of its own skin everyday and keep it moisturized, and healthy, (b) neutralize free radical oxidation and the damaging effects of excessive solar radiation and (c) keep microbes in check by the action of antimicrobial peptides secreted on the skin, (d) repair and regenerate its skin. It even regenerates some of its organs whenever damaged.
It keeps the skin moisturized, prevents skin infection, repairs wounds, promotes scar less healing, and renews the skin.
The collection of the biological ingredient is achieved with a humanely method without inflicting any harm to the little creatures.
Skin Treatment Products
BIOSKINCARE™
A natural skin care cream that triggers the regeneration of damaged cells and replenishes the lipid barrier of the skin while preventing and removing scars from burns, accidental injuries and post surgery; stretch marks; hypertrophic scars; keratois pilaris, actinic keratosis, dermatitis, psoriasis scales and all types of skin blemishes. 50 gram jar = $69.98 and for two or more 20% discount.
A natural skin cream for the reduction of keloid scars. Halts itching. Regulates dermal fibroblast proliferation and excess collagen, and thus helps to prevent and reduce scar keloids and hyperthropic scarring. Acts as a potent antioxidant and anti-inflammatory. Regulates blood vessel formation and oxygenation within the skin. Smoothes old surgery scars and rough and dry skin. 50 gram jar = $79
BIO STRETCH MARK CREAM™
Prevents stretch marks, strengthens fragile skin, firms sagging breasts and body areas and reduces cellulite. It also works for newly formed stretch marks and scars, while BIOSKINEXFOL works best for old, rough and raised marks. The base cream is the same as in BIOSKINCARE, in a more economical container, with 6 oz. but for use only on the body, not on the face, because it contains a slightly higher proportion of the biological complex which results in an invisible film that retains in moisture by occluding the area where it is applied but may feel a little tacky on the face. 4 oz (120 grams) = $79.98
BIO SKIN REJUVENATION™
Same cream base and enzymes as in BIOSKINCARE to "digest" or dissolve blemishes, speed skin turnover and tighten skin, and two added ingredients: one is a human growth factor peptide, derived from the melanocyte-stimulating-hormone. Blocks melanin synthesis, and reduces the formation of unwanted pigmentation, allowing control over skin tone and brown spots. The other is a natural plant extract that takes away dark pigmentation. Leaves skin bright and refreshed! 50 gram jar = $79
BIOSKINCLEAR™
An oil free moisturizer gel for acne, rosacea and facial scars. Heals lesions to the cells lining the hair follicles which is the root cause of inflammatory acne. Removes dead cells, unclogs sebum canals and dissolves scar tissues by enzymatic hydrolysis, without peeling. Promotes the proliferation of antimicrobials that control acne bacteria. Boosts reproduction of glycosaminoglycans, the molecules that retain water, thus truly moisturizing the skin from within. Tells the body it is being taken care off and can moderate an otherwise extreme inflammatory reaction that may end up destroying healthy skin cells and creating crater like scarring and not only the acne bacteria. 50 gram (1.76 oz) airless pump bottle $59 and 20% off for two or more.
BIOSKINEXFOL™
A home microdermabrasion cream with micro-crystals that breakdown hard, rough and old scar tissues, and allow for a deeper penetration of our natural skin moisturizing and regeneration complex contained in the microdermarasion cream. 120 gram (4 oz) jar = $89
The articles you may access from the menu below provide information from different sources about burn care, wounds, Burn Medical Care, scars and other related subjects of interest. We are working to update all of them and when they are ready this message will no longer be here.
Other Links Related to Burn Medical Care
© BIOSKINREVIVAL.com BURN SKIN TREATMENT PRODUCTS
| Burn Scars Removal - Healing Skin Dryness, Hyperpigmentation Treatment | SiteMap |
